01 - Pat chicken breasts dry with paper towels. Season both sides generously with 1 teaspoon salt and 1/2 teaspoon black pepper.
02 - In a large bowl, whisk together buttermilk, hot sauce, chopped jalapeños, and minced garlic until fully combined.
03 - Add seasoned chicken breasts to the marinade, ensuring they are completely submerged. Cover bowl and refrigerate for at least 1 hour, up to overnight for maximum flavor penetration.
04 - In a shallow dish, combine flour, cornmeal, smoked paprika, cayenne pepper, garlic powder, onion powder, 1/2 teaspoon salt, and 1/2 teaspoon black pepper. Mix thoroughly to distribute spices evenly.
05 - Remove chicken from marinade, allowing excess liquid to drip off. Dredge each piece in the breading mixture, pressing firmly to ensure coating adheres completely. Place breaded chicken on a wire rack.
06 - Pour approximately 2 inches of vegetable oil into a deep skillet or Dutch oven. Heat to 350°F, maintaining temperature throughout frying process.
07 - Fry chicken breasts in batches, cooking 6 to 8 minutes per side until golden brown and cooked through. Internal temperature must reach 165°F. Do not overcrowd the pan.
08 - Transfer cooked chicken to a wire rack or paper towels to drain excess oil. Let rest for 5 minutes before serving to allow juices to redistribute.