01 - Pat the brisket dry and evenly season all sides with kosher salt, black pepper, smoked paprika, thyme, and oregano.
02 - Heat olive oil in a large skillet over medium-high heat and sear brisket for 3 to 4 minutes per side until browned.
03 - Place the seared brisket into the slow cooker.
04 - Arrange sliced onions, carrots, celery, and minced garlic around and on top of the brisket.
05 - Whisk together beef broth, red wine (if using), tomato paste, and Worcestershire sauce, then pour evenly over the meat and vegetables.
06 - Cover and cook on low for 8 hours until the brisket is tender and easily pierced with a fork.
07 - Remove brisket from slow cooker and allow to rest for 10 minutes. Slice against the grain for optimal tenderness.
08 - Skim excess fat from the cooking juices, serve slices of brisket with vegetables, and spoon sauce over the top.