01 - Preheat your oven to 400°F. Grease a 9x13-inch casserole dish with cooking spray or olive oil.
02 - Heat a splash of olive oil in a large skillet over medium heat. Sauté diced onion for 3-4 minutes until softened. Add minced garlic and cook for 30 seconds until fragrant.
03 - Add diced chicken breast to the skillet. Cook for 5-6 minutes, stirring occasionally, until chicken is just cooked through. Remove from heat.
04 - In a large bowl, combine cream cheese, Greek yogurt, cottage cheese, mozzarella, 1/4 cup Parmesan, Italian herbs, salt, black pepper, and red pepper flakes. Mix until smooth and creamy.
05 - Fold the cooked chicken mixture, thawed spinach, and chopped artichoke hearts into the cheese sauce until evenly distributed.
06 - Spread the mixture evenly into the prepared casserole dish, smoothing the top with a spatula.
07 - In a small bowl, mix panko breadcrumbs with 2 tbsp Parmesan cheese. Sprinkle this mixture evenly over the casserole. Lightly mist with olive oil spray.
08 - Bake for 30-35 minutes until the casserole is bubbly around the edges and the topping is golden brown.
09 - Let the casserole rest for 5-10 minutes before serving to allow it to set. Garnish with fresh herbs if desired.